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Effects of Hypoxia on the Formation of Osteoclast

½ÉÇý¿µ, Á¤´Ù¿î, äâÈÆ, ÀÌ¿µ, ÀåÀº½Ä, Ã̶ֹó, È«¼ø¹Î, ¹ÚÁØ¿ì,
¼Ò¼Ó »ó¼¼Á¤º¸
½ÉÇý¿µ ( Sim Hye-Young ) - ¼­¿ï½Ã¸³º¸¶ó¸Åº´¿ø ±³Á¤°ú
Á¤´Ù¿î ( Jung Da-Un ) - ¼­¿ï½Ã¸³º¸¶ó¸Åº´¿ø º¸Ã¶°ú
äâÈÆ ( Chae Chang-Hoon ) - ³ª³ëÅ¥¾îÅØ
ÀÌ¿µ ( Lee Young ) - ÇѸ²´ëÇб³ ÀÇÇаú ´ëÇпø
ÀåÀº½Ä ( Jang Eun-Sik ) - ÇѸ²´ëÇб³ ÀÇÇаú ´ëÇпø
Ã̶ֹó ( Choi Mee-Ra ) - ÇѸ²´ëÇб³ ÀÇ°ú´ëÇÐ °­µ¿¼º½Éº´¿ø º¸Ã¶°ú
È«¼ø¹Î ( Hong Soon-Min ) - ÇѸ²´ëÇб³ °­µ¿¼º½Éº´¿ø ±¸°­¾Ç¾È¸é¿Ü°ú
¹ÚÁØ¿ì ( Park Jun-Woo ) - ÇѸ²´ëÇб³ °­µ¿¼º½Éº´¿ø ±¸°­¾Ç¾È¸é¿Ü°ú

Abstract


The vascular changes in periodontal tissues cause local hypoxia which seems to affect the periodontal tissue cells. Abrupt changes in oxygen availability within the periodontium have been suggested to have a regulatory role in alveolar bone remodeling during tooth movement, bone growth or fracture healing. The purpose of this study was to study the effects of hypoxia on formation of osteoclast responsible for bone resorption, in vitro. Primary mouse bone marrow cells were cultured in normoxic (20% O2) and hypoxic (1% O2) conditions and assayed for cellular proliferation. The results obtained were as follows:

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Osteoclast;Hypoxia

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KCI
KoreaMed